At-Home Blood Pressure Cuff Adds Value for African Americans

UT Southwestern researchers have found added value for African Americans who use a blood pressure cuff at home, augmenting benefits of the at-home tool. African Americans have a higher rate of disability and death related to high blood pressure than other groups, according to the American Heart Association. UTSW researchers analyzed the Dallas Heart Study and found that measuring blood pressure at home is more accurate, less expensive, and easier to obtain than in medical settings, where it often reads higher due to anxiety. “Our study shows that African American men and women who are taking medications to control their hypertension… Full Story

Treatment Showing Potential to Fight Deadly Kidney Disease at UTSW

Testing at UT Southwestern has shown positive results for a new treatment of polycystic kidney disease, a genetic disorder that causes multiple cysts to form on the kidney and can lead to swelling and organ failure. The study shows a 50 percent reduction in kidney size in mice following treatment. Dr. Vishal Patel, Associate Professor of Internal Medicine at UT Southwestern and senior author of the study has also led the drug to early clinical trials in humans. Autosomal dominant polycystic kidney disease impacts around 12 million people worldwide, and about half end up with the final stages of kidney failure by… Full Story

Mary Kay Foundation to Fund Cancer Fellowship at UT Southwestern

The Mary Kay Foundation will be granting $500,000 to fund a fellowship at UT-Southwestern that will fund five international postdoctoral researchers, giving them the opportunity to study cancer. “Mary Kay Ash, our founder, saw firsthand the impact that cancer had on our independent beauty consultants, their families, and women around the world,” said Ryan Rogers, board member of The Mary Kay Foundation and grandson of Mary Kay Ash via release. “It became a mission for her to eradicate cancers affecting women. Our expanded partnership with UT Southwestern will allow us to continue that lifesaving work on a global scale.” The fellowship continues… Full Story

Elderly Have a Worse Prognosis at Long-Term Acute Care Hospitals Than Advanced Cancer Patients

Fewer than 1-in-5 older adults who are transferred to a long-term acute care hospital are alive five years later, giving these individuals a worse prognosis than advanced cancer, according to researchers at UT Southwestern Medical Center and UC San Francisco. The study looked at 14,072 patients admitted to the long term care hospitals, and found the average patient spent nearly two thirds of their life in a hospital or inpatient setting and that one third died and never made it home. Only 16 percent of patients ever made it to hospice for an average of 10 days, lower than other… Full Story

CPRIT Awards $15.4 Million to OncoNano For HPV-Caused Cancer Treatment

Southlake’s OncoNano Medicine, Inc. has been awarded $15.4 million to continue to develop one of its cancer treatment candidates. The funding is from the Cancer Prevention and Research Institute of Texas will go toward pre-clinical and clinical development as well as the first phase of a trial for cancer caused by the human papilloma virus. The treatment is called ONM-500, which delivers antigens while engaging the immunity that already exists in the human body, fighting cervical, head, and neck cancers caused by HPV. CPRIT, which has awarded $2.4 billion in grants to Texas research, has funded the product which was first… Full Story

Expert: Women’s Equality in Medical Research

When it comes to Women’s Equality Day, your first thought is probably equal pay or fair treatment in the workplace. While these are incredibly important causes in our fight for equality, we should also consider equality in health care, starting with equal representation in biomedical research. Unfortunately, women, especially those who belong to minority communities, are less likely to be included in clinical trials then men in the United States. This becomes particularly important when you consider scientific assessments that every cell in the body has a sex, meaning the biological difference between men and women breaks down to a… Full Story

Caris Life Sciences Adds 500 Jobs and Space With Corporate Park in Irving

Caris Life Sciences is expanding in Irving, adding 115,000 square feet of research and development and office space while creating 500 new job opportunities. Caris Life Sciences Park will allow the company to expand beyond their work in blood-based diagnostics and molecular profiling. The new facility’s first phase should be complete in early 2020, and will include future laboratories and corporate office space. The last two phases will include additional lab space for the molecular science innovators. “Our new facilities in Irving, Texas will allow us to add to our team of experts, and enhance our ability to deliver more… Full Story

The Keto Diet is Successfully Fighting Cancer at UT Dallas

The keto diet might be a way to fight against certain cancers, according to biologists at The University of Texas at Dallas. Avoiding glucose has long been known to help fight diabetes, but restricting glucose levels in blood might also be a bulwark against cancer cells as well. The study cut glucose levels for mice with lung cancer by feeding them a ketogenic diet, pairing reduced sugar with a diabetes drug. Many cancers are suspected to be dependent on glucose as an energy source, but the research showed that squamous cell carcinoma is even more dependent than other cancers. “Both the… Full Story

UTSW Researchers Find Broader Use for Cancer Drugs

UT Southwestern researchers may have found a wider application for cancer drugs that are normally reserved for a small slice of patients. Treatment normally used for less than 10 percent of breast cancer patients may be effective in treating all cancers. The study found a biomarker that indicates when the drugs can be used to fight the broad array of cancers. “These findings could increase the patient population benefiting from these drugs by two, three, or four-fold. Up to 70 percent of breast cancer patients could now be good candidates,” said Dr. W. Lee Kraus, Director of the Green Center for… Full Story

UT Southwestern’s Gene Therapy Center Could be a Game Changer

The UT Southwestern gene therapy center should be up and running by the end of this year, and it may be an answer for the family of a young boy with a rare genetic neurological disorder who is running out of time. D CEO contributor Jason Heid shares the story in Texas Monthly.  When Joseph Hann was three, he began to lose his balance and vision, and after he experienced a grand mal seizure was diagnosed with a rare form Batten disease, which is almost always fatal in childhood. The disease attacks the nervous system, taking away a person’s ability to see,… Full Story