Watch: Two UT Southwestern Scientists Discuss Their Award-Winning Research

Two UT Southwestern Scientists have been identified as up and comers by The Academy of Medicine, Engineering and Science of Texas. Dr. Ralph DeBerardinis, Professor at the Children’s Medical Center Research Institute at UT Southwestern and Chief of the Division of Pediatric Genetics and Metabolism at UT Southwestern, and Dr. Julie Pfeiffer, Professor of Microbiology at UT Southwestern will both receive the 2019 Edith and Peter O’Donnell Award. The award honors early career researchers for their work in science, medicine, engineering, and technology innovation, and includes a $25,000 prize and an invitation to speak at their conference in January, where they will receive the award… Full Story

Local Researchers Identify Marker for Patients at Risk of Immunotherapy Side Effects

UT Southwestern researchers may have moved closer to identifying patients at greatest risk of side effects from immunotherapy treatments. Immunotherapy mobilizes the patient’s immune system to fight cancer, and researchers found that there are molecules called cytokines that signal the immune system to fire up to fight disease. If cytokines are low in a patient, that patient is more likely to develop immune-related side effects. The studies focused on a variety of cancer types and widely used immunotherapy drugs and were funded from a grant from the American Cancer Society. They will expand to multicenter clinical trials to look at… Full Story

UTSW Researchers One Step Closer to Stopping Disease Causing Thousands of Painful Tumors

Imagine having a condition that covers your body with thousands of small tumors. Not only are they disfiguring, but they itch, are painful, catch on your clothing, bleed, and can become infected. The only thing worse than the physical pain is the emotional distress of trying to hide them, if possible. The condition is called neurofibromatosis type 1, and occurs in one in 3,000 people. UT Southwestern researchers have created a model and identified a marker for the cell of origin for NF1 tumors, allowing them to learn more about how they form and possibly slow their growth. “Because of this model,… Full Story

The 2019 Breakthrough Prize Winner in Life Sciences is a Local Researcher

A UT Southwestern researcher is one of the recipients of the 2019 Breakthrough Prize, which awards achievements in the fields of physics, life sciences, and mathematics. UT Southwestern’s Zhijian “James” Chen, who also works for the Howard Hughes Medical Institute, was honored for his work in life sciences for discovering how DNA triggers immune and autoimmune responses from the interior of a cell. His research looks to improve the immune system’s defense against pathogens, malignant cells, and diseases such as lupus. Chen will win $3 million, which is one of the most generous science prizes in the world. Chen is the… Full Story

Join Us for D CEO’s Cancer-Focused Healthcare Panel Breakfast

Texas is 13th in the country in number of cancer deaths at 149 per 100,000, according to the Kaiser Family Foundation, and part of the reason Texas has such a high ranking despite being one of the most uninsured states in the country is the strength of the medical community and its ability to stay on the cutting age of cancer research and treatment. To dig deeper into these strengths, D CEO will host our second D CEO Healthcare Breakfast Panel Discussion to explore how our region is shaping cancer treatment. As Americans live longer and cancer becomes more prevalent… Full Story

UT Arlington Dedicates New Science, Engineering, and Research Facility

UT Arlington officials cut the ribbon on the university’s new Science & Engineering Innovation & Research building. The $125 million facility will focus on interdisciplinary research on major health science challenges of the day such as brain health, cancer, healthy aging, and cardiovascular health. “We want to thank our champions in the legislature, the Board of Regents, the University of Texas System leadership and the campus community for believing in our vision,” said UTA President Vistasp Karbhari. “SEIR is the embodiment of our health science focus, bringing together research neighborhoods, collaborative spaces, teaching facilities and areas where faculty, staff and… Full Story

M.D. Anderson’s Dr. James Allison Awarded Nobel Prize

Houston can call one of its top physicians a Nobel Prize winner. M.D. Anderson Cancer Center’s Dr. James P. Allison won the 2018 Nobel Prize in Physiology or Medicine for his breakthrough cancer research this week, the New York Times reports. Allison, 70, worked toward aiding the immune system’s ability to attack cancer by suppressing the proteins that resist the immune’s system’s ability to fight cancer cells. Normally, cancer treatment involves three plans of attack: surgery, radiation, and chemotherapy. But the Nobel committee at the Karolinska Institute called Allison’s immune system treatment “an entirely new principle for cancer therapy,” according… Full Story

Susan G. Komen To Fund $600,000 Grant For Breast Cancer Research At UTSW

Dr. Carlos Arteaga of UT Southwestern Medical Center is the recipient of a $600,000 Susan G. Komen organization research grant that will help him improve precision in breast cancer treatment while preventing drug resistance. Arteaga serves as the Director of the Harold C. Simmons Comprehensive Cancer Center and Associate Dean of Oncology Programs at UT Southwestern. While 90 percent of breast cancer patients survive for 5 years, more than 40,000 women still die from the disease each year in the United States, according to the National Cancer Institute. According to the Advanced Pharmaceutical Bulletin journal, 90 percent of failures in chemotherapy… Full Story

After ‘Big Bang’ Discovery, UTSW Center for Alzheimer’s Gets $700K Boost From Aging Mind Foundation

The Aging Mind Foundation has handed over a $700,000 check to UT Southwestern Medical Center’s Center for Alzheimer’s and Neurodegenerative Diseases and the Peter O’Donnell Jr. Brain Institute to help continued efforts in finding the root cause of Alzheimer’s and other forms of dementia. It’s the largest chunk of money put together yet by the five-year-old nonprofit, which gives to a different dementia research-focused philanthropy each year. Aging Mind has given about $2 million overall, with an emphasis on programs that look specifically at the cause of Alzheimer’s. “You can’t do anything else correctly until you know what’s causing it,”… Full Story

Two UT Southwestern Faculty Members Receive Endocrine Society Laureate Awards

A couple of UT Southwestern Medical Center faculty members learned this week that they’re winners of heralded Laureate Awards from the Endocrine Society. Dr. Helen Hobbs, director of the Eugene Mcdermott Center for Human Growth and Development, takes home the 2019 Gerald D. Aurbach Award for Outstanding Translational Research. It’s the latest in a very decorated stretch for Hobbs, whose work led to the development of a new class of drugs for treating high cholesterol by identifying how certain genetic variants impact cardiometabolic health. Carole Mendelson, a professor of biochemistry and obstetrics and gynecology, receives the Sidney H. Ingbar Distinguished… Full Story